通过矿物沉积产生的"生物活性"材料诱导牙重矿化:一个体外研究
Marta Kunert1, Ireneusz Piwonski2, Louis Hardan3
1Department of General Dentistry, Medical University of Lodz, 251 Pomorska St., 92-213 Lodz, Poland.
Nanomaterials (Basel, Switzerland)
|February 9, 2024
概括
与酸水泥 (CSM) 相比,现代基于树脂的生物活性材料对牙的重矿化能力有限. CSM有效地促进了在牙-物质接口的矿物沉积,这表明它具有更高的修复潜力.
科学领域:
- 生物材料科学 生物材料科学
- 牙科材料 牙科材料
- 矿化研究 矿化研究
背景情况:
- 基于树脂的材料 (RBM) 越来越多地被销售为"生物活性",具有牙重矿化潜力.
- 酸水泥 (CSM) 以其诱导矿物沉积和促进愈合的能力而闻名.
研究的目的:
- 评估和比较现代RBM与CSM的牙重矿化能力.
- 通过使用先进的分析技术,评估材料-牙接口的矿物沉积.
主要方法:
- 经过测试的CSM (ProRoot MTA,MTA Angelus,Biodentine,TheraCal LC) 和RBM (ACTIVA Bioactive,ACTIVA Presto,Predicta Bioactive Bulk) 已经通过了测试,这些产品中使用的产品包括:
- 通过扫描电子显微镜 (SEM) 和能量分散式X射线光谱 (EDX) 评估矿物沉量.
- 在基线和浸入模拟体液28天后分析的标本,计算Ca/P比率.
主要成果:
- CSM显示了显著的表面降水,有效地填补了材料和牙之间的差距.
- 环形机械表现出最小的矿物沉,并且没有重新矿化牙-材料接口.
- 与RBM相比,CSM在诱导矿物沉积方面表现出更好的能力.
结论:
- 现代"生物活性"的RBM在诱导牙重矿化方面不如CSM有效.
- CSM更适合在牙-材料界面促进修复过程.
- 这项研究强调了CSM的优越矿化能力,而不是当前的RBM.
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