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Updated: Jul 4, 2025

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
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阿片类受体通过β-阿雷斯通路影响人类角质细胞中的日间节律

Paul Bigliardi1,2, Seetanshu Junnarkar3, Chinmay Markale1,2

  • 1Department of Dermatology, University of Minnesota, Minneapolis, MN 55455, USA.

Cells
|February 9, 2024
PubMed
概括

德尔塔阿片类受体 (DOPr) 的激活通过改变昼夜节律来延迟PER2基因表达. 这种机制涉及β-arrestin-1和染色质重塑,可能会将皮肤伤口愈合与癌症发展联系起来.

关键词:
这是一种β-arrestin.昼夜节律 昼夜节律质细胞 (keratinocyte) 是一种细胞.在阿片类受体的阿片类受体.

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