大电压CT扫描参数对线下自适应性辐射疗法的影响
Kento Hoshida1, Ayumu Ohishi2, Asumi Mizoguchi2
1Department of Radiology, Kurume University Hospital, 67 Asahimachi, Kurume, Fukuoka, 830-0011, Japan. hoshida_kento@kurume-u.ac.jp.
Radiological physics and technology
|February 9, 2024
概括
托莫疗法 (TomoTherapy) 是一种治疗方法.
科学领域:
- 医学物理 医学物理
- 辐射瘤学 辐射瘤学
- 影像科学 影像科学
背景情况:
- 托莫疗法利用图像导向放射治疗 (IGRT) 与大电压CT (MVCT) 进行精确的患者定位.
- 在治疗期间获得的MVCT图像为回顾性剂量评估和适应性辐射疗法 (ART) 提供了潜力.
- 不同的MVCT扫描参数对剂量计算和可变形图像记录 (DIR) 准确性的影响需要调查.
研究的目的:
- 在18种不同的MVCT成像条件下评估剂量计算和DIR的准确性.
- 评估MVCT扫描参数 (获取距离,切片间隔) 对DIR精度的影响.
- 为了确定MVCT扫描参数对适应性放射治疗 (ART) 结果的影响.
主要方法:
- 在18个MVCT条件下为密度校准表 (IVDTs) 获得的图像值.
- 在MVCT图像上进行了剂量重新计算和DIR,图像是胸部幻影与食道IMRT计划.
- 使用平均距离到一致 (MDA) 和Dice相似系数 (DSC) 评估DIR准确性.
主要成果:
- 在18个MVCT条件下,IVDT结果没有发现显著差异.
- 剂量重新计算显示了食道IMRT计划的最小差异.
- 随着采集音调和切片间隔的增加,DIR准确度下降 (增加MDA,减少DSC).
结论:
- MVCT扫描参数对剂量计算准确性和整体ART的影响最小.
- DIR准确性对采集距和切片间隔敏感,影响其在ART中的可靠性.
- 虽然剂量分配的变化很小,但建议仔细选择MVCT参数,以获得最佳的DIR.
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