一个非平衡消散系统,具有可调节的分子燃料流量
Jiayu Yang1, Tengfang Zhang1, Linghao Zhang1
1College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China. xinsu@mail.buct.edu.cn.
Nanoscale
|February 9, 2024
概括
这项研究介绍了一种使用DNA纳米技术控制燃料流量的生物系统,模仿细胞能量通路. 这种可调节的系统调节非平衡状态和仿生过程,如纳米粒子组装.
科学领域:
- 生物模拟学和合成生物学
- 纳米技术和材料科学 材料科学
背景情况:
- 细胞通过间接燃料 (IF) 利用利用大分子燃料,通过糖解等途径调节小分子燃料生成 (燃料流).
- 细胞中的分散网络和结构是由这些能量转化过程驱动的.
- 直接燃料利用 (DF) 涉及直接获得和使用小分子燃料.
研究的目的:
- 使用动态DNA纳米技术开发一个可调节燃料流的生物消散系统.
- 为了研究燃料流量与非平衡过渡状态的强度之间的关系.
- 证明系统能够调节仿生过程的能力,例如纳米粒子组装.
主要方法:
- 设计了一个动态DNA纳米技术系统,以创建一个生物消散系统.
- 通过调节链位移和酶反应速度来控制燃料流量.
- 利用该系统调节金纳米粒子 (AuNPs) 的组装和拆卸动态.
主要成果:
- 对燃料流量和非平衡过渡状态的强度进行了可调节的控制.
- 在一定范围内发现燃料流量和瞬态强度之间的正相关性,在和后变为负.
- 展示了AuNP组装/拆卸速度和强度的生物模拟调节,类似于微管子动态.
结论:
- 开发的散射系统提供可调节的分子燃料流量,使得可以精确控制非平衡动力学.
- 这个系统成功地仿真了生物调节过程,以纳米粒子组装为例.
- 这项技术在仿生学,合成生物学,智能材料,生物传感和人工细胞等领域具有很大的应用潜力.
更多相关视频
07:24Combustion Chemistry of Fuels: Quantitative Speciation Data Obtained from an Atmospheric High-temperature Flow Reactor with Coupled Molecular-beam Mass Spectrometer
Published on: February 19, 2018
10.1K
10:29Experimental Methodology for Estimation of Local Heat Fluxes and Burning Rates in Steady Laminar Boundary Layer Diffusion Flames
Published on: June 1, 2016
11.8K
相关概念视频
The Carnot Cycle
2.9K
Converting work to heat is an irreversible process, and the purpose of a heat engine is to reverse the effect partially. Heat engines aim to increase the efficiency of the reversal, that is, maximize the work retrieved from heat. If the efficiency of a heat engine were 100%, it would imply reversing the process completely without introducing any other effect. Thus, it would violate the second law of thermodynamics.
What could be the theoretical limit to the efficiency of a heat engine? The...
What could be the theoretical limit to the efficiency of a heat engine? The...
2.9K
Non-equilibrium in the Cell
4.4K
An important concept in studying metabolism and energy is that of chemical equilibrium. Most chemical reactions are reversible. They can proceed in both directions, releasing energy into their environment in one direction, and absorbing it from the environment in the other direction. The same is true for the chemical reactions involved in cell metabolism, such as the breaking down and building up of proteins into and from individual amino acids, respectively. Reactants within a closed system...
4.4K
The Nernst Equation
40.8K
Nonstandard Reaction Conditions
The interconnection between standard cell potentials and various thermodynamic parameters such as the standard free energy change ΔG° and equilibrium constant K has been previously explored. For example, a redox reaction involving zinc(II) and tin(II) ions at 1 M concentration with Eºcell = +0.291 V and ΔG° = −56.2 kJ is spontaneous.
The interconnection between standard cell potentials and various thermodynamic parameters such as the standard free energy change ΔG° and equilibrium constant K has been previously explored. For example, a redox reaction involving zinc(II) and tin(II) ions at 1 M concentration with Eºcell = +0.291 V and ΔG° = −56.2 kJ is spontaneous.
40.8K
Flame Photometry: Overview
592
Flame photometry, also known as flame emission spectrometry, is a technique used for the qualitative and quantitative analysis of elements present in a sample using a flame as the source of excitation energy. The concept of flame photometry was realized in the early 1860s by Kirchhoff and Bunsen, who discovered that specific elements emit characteristic radiation when excited in flames. The first instrument developed for this purpose was used to measure sodium (Na) in plant ash using a Bunsen...
592
