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在衰老和PLN-R14del心肌病症中,DWORF的删除不会影响心脏功能

Nienke M Stege1, Vivian Oliveira Nunes Teixeira1, Sietske N Zijlstra1

  • 1Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

American journal of physiology. Heart and circulatory physiology
|February 9, 2024
PubMed
概括

删除矮人开放阅读框架 (DWORF) 基因不会使心肌病症恶化,这种心肌病症是由小鼠中的斯福兰班 (PLN) R14del变体引起的. 在老化过程中,DWORF对正常的心脏功能并不重要.

关键词:
杜沃夫的淘汰赛心肌病性心脏病 - 心肌病性心脏病心脏衰竭是因为心脏衰竭.第14章 德尔的胺是一种酸盐.

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