Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

610
The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
610
Mass Analyzers: Overview01:13

Mass Analyzers: Overview

670
The mass analyzer is a crucial component of the mass spectrometer. In the ionization chamber, the vaporized sample is bombarded with a high-energy electron beam to generate a radical cation and further fragment into neutral molecules, radicals, and cations. A series of negatively charged accelerator plates accelerate the cations into the mass analyzer. The mass analyzer separates ions according to their mass-to-charge (m/z) ratios and then directs them to the detector. The common types of mass...
670
Capillary Electrophoresis: Instrumentation01:20

Capillary Electrophoresis: Instrumentation

234
Capillary electrophoresis instrumentation typically consists of several key components. A high-voltage power supply generates the electric field necessary for the separation by connecting to an anode (the positively charged electrode) and a cathode (the negatively charged electrode) located in buffer reservoirs at each end of the capillary tube. The system includes a sample vial, a fused silica capillary tube coated with polyimide for mechanical strength through which the sample components...
234

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Genomic evolution and natural history of myeloproliferative neoplasms on therapy.

Cancer discovery·2026
Same author

Belantamab mafodotin, bortezomib, and dexamethasone for RRMM in the Japan expansion cohort of the phase 3 DREAMM-7 trial.

International journal of hematology·2026
Same author

Cost-effective affinity support for the rapid separation of bacteria from complex food matrices.

Frontiers in microbiology·2025
Same author

Belantamab mafodotin plus bortezomib and dexamethasone in patients with relapsed or refractory multiple myeloma (DREAMM-7): updated overall survival analysis from a global, randomised, open-label, phase 3 trial.

The Lancet. Oncology·2025
Same author

Transcriptomic Analysis of <i>Campylobacter jejuni</i> Following Exposure to Gaseous Chlorine Dioxide Reveals an Oxidative Stress Response.

International journal of molecular sciences·2025
Same author

Multiplexed Detection of <i>Salmonella</i>, <i>Escherichia coli</i>, <i>Campylobacter,</i> and <i>Listeria</i> in Raw Poultry.

Foods (Basel, Switzerland)·2025

相关实验视频

Updated: Jul 4, 2025

Capture Compound Mass Spectrometry - A Powerful Tool to Identify Novel c-di-GMP Effector Proteins
12:11

Capture Compound Mass Spectrometry - A Powerful Tool to Identify Novel c-di-GMP Effector Proteins

Published on: March 29, 2015

11.7K

磁性捕获装置用于大批量样本分析.

Cheryl M Armstrong1, Joseph A Capobianco1, Joe Lee1

  • 1United States Department of Agriculture, Agriculture Research Service, Eastern Regional Research Center, Wyndmoor, Pennsylvania, United States of America.

PloS one
|February 9, 2024
PubMed
概括
此摘要是机器生成的。

一种新的基于螺杆的免疫磁分离 (IMS) 方法克服了大型或复杂样品的传统超对磁粒子的局限性. 这种技术提供了高效的混合和快速回收,无需专门的设备或颗粒损失.

更多相关视频

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics
07:42

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics

Published on: February 19, 2017

8.8K
Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

9.6K

相关实验视频

Last Updated: Jul 4, 2025

Capture Compound Mass Spectrometry - A Powerful Tool to Identify Novel c-di-GMP Effector Proteins
12:11

Capture Compound Mass Spectrometry - A Powerful Tool to Identify Novel c-di-GMP Effector Proteins

Published on: March 29, 2015

11.7K
Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics
07:42

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics

Published on: February 19, 2017

8.8K
Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

9.6K

科学领域:

  • 生物技术是生物技术.
  • 材料科学 材料科学 材料科学
  • 分析化学 分析化学

背景情况:

  • 传统的免疫磁分离 (IMS) 使用超偏磁粒子,对许多应用有效.
  • 对于大容量,粘性或颗粒丰富的样本存在限制,这是由于粒子回收的高场梯度要求.
  • 这些局限性可能会阻碍IMS在复杂的生物矩阵中的效率和适用性.

研究的目的:

  • 开发一种新的免疫磁性分离技术,克服传统超偏磁粒子的局限性.
  • 引入一种利用宏观脊柱与生物识别元素相结合的方法,用于增强IMS.
  • 解决与IMS中的大容量和复杂样本矩阵相关的挑战.

主要方法:

  • 生物识别元素与宏观的皮雷克斯脊柱结合.
  • 使用spinbar作为磁性组件用于免疫磁性分离.
  • 在粒子回收和样本处理中利用spinbar的磁性.

主要成果:

  • 基于spinbar的方法证明了有效的混合能力.
  • 在没有专门的设备的情况下,可以实现几乎即时的回收.
  • 在加工过程中没有观察到磁性颗粒的损失,并减少了样本矩阵转移.
  • 这种技术在用复杂矩阵进行大体积测定时被证明是有效的.

结论:

  • 宏观的脊柱为免疫磁性分离提供了超级磁性粒子的可行替代方案.
  • 这种新的方法提高了对具有挑战性的样本类型的IMS效率.
  • 基于Spinbar的IMS为大批量和复杂样本分析提供了具有成本效益和强大的解决方案.