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Updated: Jul 4, 2025

Heteromulticellular Stromal Cells in Scaffold-free 3D Cultures of Epithelial Cancer Cells to Drive Invasion
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Heteromulticellular Stromal Cells in Scaffold-free 3D Cultures of Epithelial Cancer Cells to Drive Invasion

Published on: April 4, 2025

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单细胞分析确定了NOTCH3-介导的干细胞之间的相互作用,促进微环境重塑和入侵肺腺癌

Handan Xiang1, Yidan Pan2, Marc A Sze2

  • 1Discovery Immunology, Merck & Co., Inc., Cambridge, Massachusetts.

Cancer research
|February 9, 2024
PubMed
概括

NOTCH3信号传递在肺腺癌层中促进癌症的进展和低生存率. 向NOTCH3可以通过减少原和侵袭来改善免疫治疗反应.

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