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Updated: Jul 4, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

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一个带有N-异环环的Pt(II) 复合体诱导了卵巢癌中的铁细胞死亡

Xiaomin Shen1, Yue Peng1, Haixia Zhou2

  • 1School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, PR China.

Journal of inorganic biochemistry
|February 9, 2024
PubMed
概括

一种新的复合物,PtQ,通过诱导活性氧物种 (ROS) 和铁亡,显示出对抗卵巢癌的希望. 这种新型药物可能会克服西斯的抗药性机制.

关键词:
细胞毒性 细胞毒性造成的DNA损伤是DNA损伤.铁化是铁化的一种.脂质过氧化过氧化抑制了PARP1的发生.Pt(II) 综合体的使用情况.

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