在循环疲劳和变速负荷下纤维素凝块骨折
Shiyu Liu1, Aram Bahmani1, Farshid Ghezelbash1
1Department of Mechanical Engineering, McGill University, 817 Sherbrooke St W, Montreal, QC H3A 0C3, Canada.
Acta biomaterialia
|February 9, 2024
概括
纤维素凝块的疲劳值为1.66 J/m2,这对于理解循环负荷下血液凝块机制至关重要. 这项研究揭示了它们的断裂行为对负载幅度和速度敏感.
科学领域:
- 生物材料科学 生物材料科学
- 材料机械学 材料机械学
- 生物物理学的生物物理.
背景情况:
- 纤维素凝块是控制血块机械反应的必不可少的纤维质材料.
- 在生理负荷下了解纤维素凝块骨折对于血液静止和血栓形成至关重要.
- 在周期性和可变速率负载下,断裂行为在很大程度上仍然没有特征.
研究的目的:
- 在循环疲劳和单调的变速负载下描述纤维素凝块的断裂特性.
- 为了确定纤维素凝块的疲劳值和取决于速度的断裂性.
- 根据其等级结构开发解释纤维素凝块骨折行为的模型.
主要方法:
- 对纤维素凝块进行循环疲劳负荷测试.
- 在纤维素凝块上进行单调的变速负荷测试.
- 半经验模型使用3D形态计量量化.
- 粘弹性断裂建模. 粘弹性断裂建模.
主要成果:
- 纤维素凝块的疲劳值为1.66 J/m2,明显低于整体骨折性15.8 J/m2.
- 断裂行为对周期性负载幅度和负载率敏感.
- 断裂性表明速度依赖,归因于粘性弹性.
结论:
- 纤维素凝块骨折受负荷历史和速度的影响,具有明显的疲劳值.
- 一个半经验模型成功地合理化了基于纤维素纤维层次的疲劳值.
- 粘弹性特性控制了依赖于速率的断裂性,提供了与水凝和生物组织相比的见解.
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