在中东的前列腺癌呈现和管理
Mutlay Sayan1,2, Astrid Langoe3, Ozlem Aynaci4
1Brigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. msayan@bwh.harvard.edu.
BMC urology
|February 9, 2024
概括
在中东,大多数男性在出现症状后才被诊断出晚期前列腺癌,这凸显了对这种常见恶性瘤进行更好的查和早期干预策略的需要.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 前列腺癌是全球重要的健康问题.
- 关于中东地区前列腺癌的呈现和治疗的数据有限.
- 这项研究解决了该地区的知识差距.
研究的目的:
- 为了调查前列腺癌在中东地区的初始临床表现.
- 描述该地区前列腺癌的管理模式.
- 建立未来研究和干预的基准.
主要方法:
- 六个中东国家的机构数据库的回顾性审查.
- 包括2021年被诊断患有前列腺癌的1,136名患者.
- 人口,临床和治疗变量的描述性分析.
主要成果:
- 诊断时的中位数年龄为70岁.
- 78%的诊断是由于症状呈现而产生的,而不是常规查.
- 显著比例的患者出现了晚期疾病 (35%T3/T4,54%IV期) 和高格里森评分 (50%≥8).
- 值得注意的是,20-22%的患者没有接受治疗,无论转移状态如何.
结论:
- 在中东,前列腺癌的诊断往往发生在较晚的阶段,由症状呈现驱动.
- 相当多的患者没有接受治疗,这表明在护理方面存在潜在的障碍或挑战.
- 进一步的研究至关重要,以了解这些趋势的原因,并制定有针对性的干预措施.
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