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Updated: Jul 4, 2025

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function
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Published on: November 4, 2016

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T-bet+ B细胞通过TLR-依赖的机制被内源逆转录病毒激活和控制

Eileen Rauch1,2, Timm Amendt1,3, Aleksandra Lopez Krol1

  • 1Institute of Immunology, Philipps-Universität Marburg, 35043, Marburg, Germany.

Nature communications
|February 9, 2024
PubMed
概括

内源逆转录病毒 (ERVs) 触发了针对ERV-GFP的自身免疫B细胞反应,揭示了一个新的免疫监测机制. 这一发现突出了ERVs作为疾病的潜在驱动因素和癌症免疫治疗的目标.

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