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Bone Remodeling

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

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针对骨缺陷进行定制的三维印制陶骨移植:一项前性随机研究.

Na-Hyun Kim¹, Byoung-Eun Yang^2,3,4,5, Sung-Woon On^4,5,6

¹Department of Conservative Dentistry, Hallym University Sacred Heart Hospital, Anyang, 14066, Republic of Korea.

Scientific reports

|February 9, 2024

概括

定制的3D打印骨移植显示了指导骨再生的前景. 与传统的块骨移植相比,这种方法导致了更高的骨体积和更少的组织表面.

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科学领域:

口腔和牙面部外科手术
生物材料科学生物材料科学
再生医学是一种再生医学.

背景情况:

拔牙后膜骨的再吸收限制了植入物外科手术的选择.
全塑性骨移植材料为骨增强提供了可定制的解决方案.
计算机辅助设计和制造促进了个性化骨移植的制造.

研究的目的:

为了评估定制3D打印的全塑性骨材料用于指导骨再生的临床有效性.
为了比较3D打印患者定制骨移植与传统块骨移植的结果.

主要方法:

一项随机对照试验,涉及60名患者,需要为牙科植入物增加骨.
参与者被随机分配,接受3D打印的定制骨移植或传统的块骨移植.
在植入物安装之前,移植后5个月进行了组织学和放射学评估.

主要成果:

3D打印的定制骨移植组显示出明显更高的骨体积百分比.
与对照组相比,实验组的组织表面积较小.
在整体骨体积,骨表面,骨表面/体积比,骨表面密度或骨矿物质密度方面没有发现显著差异.

结论:

定制3D打印的全塑性骨移植材料是指导骨再生的可行替代方案.
这项技术提供了方便,并可能减少患者在骨移植手术中的不适.
这些发现支持使用3D打印定制骨移植用于更简单的骨增强病例.