饮食炎症指数与孕妇骨矿物质密度变化之间的关联:中国的一项前性研究
Xiaoyu Zhu1,2, Yalin Zhou1, Zhang Wen1
1Department of Nutrition and Food Hygiene, School of Public Health, Peking University, No. 38 Xueyuan 7 Road, Beijing 100191, China.
Nutrients
|February 10, 2024
概括
孕妇饮食炎症指数 (DII) 较高与骨矿物质密度 (BMD) 损失增加和IL-6水平较高有关. 降低DII可能有助于在怀孕期间保持BMD.
科学领域:
- 营养科学 营养科学
- 骨健康研究 骨健康研究
- 孕产妇健康研究 母亲健康研究
背景情况:
- 饮食炎症指数 (DII) 量化了饮食的炎症潜力.
- 骨矿物质密度 (BMD) 在怀孕期间对母亲和胎儿的健康至关重要.
- 了解孕妇群体对BMD的饮食影响对于公共健康至关重要.
研究的目的:
- 调查中国孕妇的DII与骨质量变化之间的关联.
- 探索DII,血清炎症标志物和BMD之间的关系.
- 提供基于证据的饮食建议,以保持怀孕期间的骨健康.
主要方法:
- 研究了一组由289名孕妇组成的队列.
- 血清炎症因子和超声波BMD在三个月内被测量.
- 从食物频率问卷中计算DII分数,并对三级动物进行分析.
主要成果:
- 较高的DII分数与增加的总能量摄入量和血清中白血素-6 (IL-6) 的升高相关.
- 较低的DII分数与更高的BMDT分数和Z分数有关.
- 在对共变量进行调整后,DII与母亲的骨质量损失有积极的关系.
结论:
- 在孕妇中,DII与血清IL-6水平有积极的关联.
- 较高的DII分数表明怀孕期间骨质流失的风险更大.
- 建议采用较低DII的饮食来保持孕妇的BMD.
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