酵母蛋白对小鼠肠道微生物群的影响,与大豆蛋白和乳清蛋白分离物相比
Xuewei Zhou1,2,3, Li Liang1,2,3, Baoguo Sun1,2,3
1Key Laboratory of Geriatric Nutrition and Health, Beijing Technology and Business University, Ministry of Education, Beijing 100048, China.
Nutrients
|February 10, 2024
概括
酵母蛋白 (YP) 补充剂通过增强乳腺免疫力和减少炎症,改善了小鼠的肠道健康. YP还丰富了有益的肠道细菌,表明它有可能作为肠道健康的饮食干预措施.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 营养科学 营养科学
背景情况:
- 饮食蛋白质来源影响肠道微生物群和宿主健康.
- 了解不同蛋白质分离物对肠道免疫力的影响至关重要.
研究的目的:
- 研究酵母蛋白 (YP),大豆蛋白分离物 (SPI) 和乳清蛋白分离物 (WPI) 对小鼠肠道微生物群和肠道免疫的影响.
主要方法:
- 在28天的时间里,小鼠接受了YP,SPI或WPI的输入.
- 评估的体重,阴道形态,紧接口蛋白质,免疫球蛋白 (IgA,IgM,IgG),细胞因子 (IL-10,IL-6),谷氨过氧化酶 (GSH-Px) 和肠道微生物群组成.
主要成果:
- 补充YP增强了叶形态和上调紧结蛋白质.
- 在YP组中观察到IgA,IgM,IgG,IL-10和GSH-Px的水平增加.
- YP的使用导致IL-6水平的显著降低和有益细菌的丰富,包括Parabacteroides,Prevotella和Pseudobutyrivibrio.
结论:
- 酵母蛋白显示出改善肠道免疫力和调节炎症反应的潜力.
- 补充YP对肠道微生物群的组成产生积极影响,增加有益细菌.
- 这些发现表明YP是增强肠道健康的有希望的饮食成分.
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