胰腺炎和胰腺癌之间的诊断区别:一个范围审查
Fusi Madela1, Lucien Ferndale1, Colleen Aldous1
1Department of Surgery, School of Clinical Medicine, College of Health Sciences, University of KwaZulu-Natal, Durban 4000, South Africa.
Diagnostics (Basel, Switzerland)
|February 10, 2024
概括
从胰腺癌区分胰腺炎仍然是一个挑战. 最近的审查强调了生物标志物和成像技术,但在预测慢性胰腺炎进展和区分这些疾病方面仍然存在知识差距.
科学领域:
- 胃肠道学和瘤学
- 诊断成像和生物标志物
背景情况:
- 胰腺炎 (急性和慢性) 和胰腺癌显著影响胰腺健康.
- 慢性胰腺炎,在约15%的病例中发展,带有风险,包括糖尿病和胰腺癌,吸烟和年龄是关键因素.
研究的目的:
- 综合最近 (2017-2022) 关于区分胰腺炎和胰腺癌的文献.
- 确定有关生物标志物和成像用于诊断和风险评估的知识差距.
主要方法:
- 关于胰腺炎和胰腺癌之间的诊断区分的出版物的范围审查.
- 专注于生物标志物 (例如,便弹性酶-1,化学激素) 和成像 (CT,MRI,EUS,PET).
主要成果:
- 非侵入性生物标志物和先进的成像显示出希望,但准确的差异化,特别是胰腺头部质量,仍然很困难.
- 现有的方法难以明确区分慢性胰腺炎和癌症.
结论:
- 胰腺炎与胰腺癌的准确诊断需要进一步的研究.
- 关于基因病理学,成像学和预测慢性胰腺炎进展为癌症的生物标志物的知识差距仍然存在.
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