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Updated: Jul 3, 2025

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线粒体功能障碍,氧化应激和器官间错误沟通在T2D进展中

Rajakrishnan Veluthakal1, Diana Esparza1, Joseph M Hoolachan1

  • 1Department of Molecular and Cellular Endocrinology, Arthur Riggs Diabetes & Metabolism Research Institute, City of Hope Beckman Research Institute, 1500 E. Duarte Rd, Duarte, CA 91010, USA.

International journal of molecular sciences
|February 10, 2024
PubMed
概括

氧化应激和线粒体功能障碍促使2型糖尿病 (T2D) 发病,无论是否首先发生胰岛素抵抗或β细胞功能障碍. 细胞之间的细胞外囊泡通信加剧了这种损伤,导致糖尿病前期和T2D.

关键词:
细胞外囊泡中的细胞外囊泡.胰岛素耐药性是一种胰岛素耐药性.岛屿小岛的β细胞线粒体中的线粒体.氧化应激是一种氧化应激.在糖尿病前期,糖尿病前期.2 型糖尿病 2 型糖尿病

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