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在视网膜退行性疾病中,小细胞外囊泡和氧化病理生理机制

Francisco J Romero1, Manuel Diaz-Llopis2, M Inmaculada Romero-Gomez3

  • 1Hospital General de Requena, Conselleria de Sanitat, Generalitat Valenciana, 46340 Requena, Spain.

International journal of molecular sciences
|February 10, 2024
PubMed
概括

小细胞外囊泡通过影响氧化应激和血管生成,在视网膜退行性疾病中发挥关键作用. 它们的载荷和释放受到细胞条件的影响,影响糖尿病视网膜病变等疾病的视力丧失.

关键词:
自自是自的过程.外基因组是外基因组的组成部分.微RNAs 是一个微型RNA.氧化应激是一种氧化应激.视网膜疾病 视网膜疾病

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DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...