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脊柱瘤手术治疗后的长期功能结果:基于人口的队列研究

Aman Singh¹, Alexander Fletcher-Sandersjöö^1,2, Victor Gabriel El-Hajj¹

¹Department of Clinical Neuroscience, Karolinska Institute, 171 76 Stockholm, Sweden.

|February 10, 2024

概括

手术切除脊髓神经瘤显著改善神经功能,特别是膀控制. 总体切除是获得更好的结果和防止瘤再生的关键.

科学领域:

神经外科神经外科
在瘤学瘤学.
脊髓医学脊髓医学

背景情况:

脊髓神经瘤是第二个最常见的脊髓内瘤,由于脊髓压缩,可以导致神经缺陷.
手术切除是主要的治疗方法,需要了解影响患者结果的因素.

研究的目的:

确定脊髓神经瘤手术治疗后有利结果的术前和术后预测因素.
评估手术切除对神经功能和症状解决的影响.

主要方法:

从2006年至2020年期间接受脊柱神经瘤治疗的成年患者的医疗记录和成像数据的回顾性审查.
使用修改后的麦考米克尺度 (mMC) 评估神经改善,并评估运动,感觉,步态,膀和疼痛变化.

主要成果:

在运动,感觉,行走,膀功能和疼痛方面观察到显著的术后改善 (p < 0.001).
膀功能障碍显示出改善率最高,所有病例的完整解决.
总切除 (GTR) 与神经状况改善和无进展生存率增加有关.

结论:

脊髓神经瘤的手术切除会导致显著的神经系统改善,特别是膀功能.
总切除是实现有利的长期结果和最大限度地减少瘤复发或再生的关键因素.

关键词:

神经外科神经外科手术斯瓦诺马斯克人的一个问题.脊椎神经瘤 (spinal schwannoma) 是一个脊柱脊柱脊柱脊柱脊柱

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