2型糖尿病老年人中的糖尿病视网膜病变:全国纵向注册研究
Ali Sharif1,2, Daniel R Smith3, Karl-Johan Hellgren1,4
1School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Acta ophthalmologica
|February 10, 2024
概括
糖尿病视网膜病变 (DR) 的患病率在10年内在患有2型糖尿病的老年人中保持稳定. 糖尿病持续时间和血糖控制等风险因素是关键因素,但年龄和性别也会影响该人群的DR风险.
科学领域:
- 眼科和内分泌学 眼科和内分泌学
- 老年医学和糖尿病护理
背景情况:
- 2型糖尿病影响着越来越多的老年人群.
- 糖尿病视网膜病变 (DR) 是糖尿病的一个重要并发症.
- 了解老年人DR对于公共卫生至关重要.
研究的目的:
- 确定80岁及以上2型糖尿病患者糖尿病视网膜病变 (DR) 的患病率,发病率和危险因素.
- 分析年龄,性别,糖尿病持续时间和血糖控制如何影响老年人DR风险.
主要方法:
- 来自瑞典国家糖尿病登记处 (2008-2017) 的141,158名2型糖尿病患者的分析.
- 根据年龄分层计算DR流行和发病率.
- 使用纵向二元物流回归模型来评估风险因素.
主要成果:
- 在整个10年的研究期间,DR患病率稳定在33.6%左右 (336.2/1000名患者).
- 原始DR发病率为8.85% (88.5/1000患者年),随着年龄的增长而下降.
- 女人从83岁开始增加了DR风险,糖尿病持续时间较长,血糖控制较差加快了DR的发生.
结论:
- 尽管DR患病率稳定,但日益增长的老年糖尿病人群需要加强查和眼睛护理.
- 传统的风险因素 (糖尿病持续时间,血糖控制) 在老年人中仍然很重要.
- 年龄和性别是2型糖尿病老年人DR风险的重要改变因素.
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