在内皮角质塑性术后,与眼内压相关的副作用
Morten B M Madsen1, Anders Ivarsen1, Niklas Telinius1
1Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.
Acta ophthalmologica
|February 10, 2024
概括
与透镜植入相结合内皮角质整形 (EK) 的法化与单独白内障提取相比,并没有对视网膜神经纤维层 (RNFL) 厚度产生负面影响. 手术后12个月,瞳孔功能和直径在组之间保持了可比性.
科学领域:
- 眼科医生 眼科 眼科
- 角膜外科手术 角膜外科手术
- 视网膜成像 视网膜成像
背景情况:
- 福克斯内皮质和白内障通常需要联合手术干预.
- 内皮角膜整形 (EK) 技术旨在恢复角膜清晰度,同时保持眼睛结构.
- 评估EK对眼神经等相邻眼组织的影响至关重要.
研究的目的:
- 为了比较单独与透镜植入后的光纤化 (phacoemulsification) 和结合内皮角膜成形 (endothelial keratoplasty) (EK) 后的环囊状视网膜神经纤维层 (RNFL) 厚度.
- 在接受这些手术的患者中评估瞳孔功能和直径.
主要方法:
- 一个随机的,单面膜试验的二次分析,涉及72名患有Fuchs内皮和白内障的患者.
- 患者被分配到超薄的Descemet的剥离自动化内皮皮质切除术 (UT-DSAEK) 或Descemet的膜内皮质切除术 (DMEK).
- 包括40名患者的对照组 (仅白内障提取[CE]);所有患者都进行了化和透镜植入.
主要成果:
- 手术后12个月,EK和CE组之间的RNFL厚度是可比的.
- 瞳孔功能 (scotopic和 photopic瞳孔直径,收缩速度) 在EK和CE组之间是相似的.
- 用重新泡泡治疗的患者显示了显著较小的scotopic瞳孔直径.
结论:
- 内皮角膜整形 (EK) 似乎不会对RNFL的厚度产生负面影响,而仅仅在12个月内进行白内障提取 (CE).
- 虹膜功能和瞳孔直径在外科手术后的EK和CE组之间是可比的.
- 进一步的研究可能会探索重新泡对瞳孔动态的具体影响.
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