脊柱fMRI显示了椎脊髓中功能连接网络的细分组织:一个测试-重新测试可靠性研究
Olivia S Kowalczyk1,2, Sonia Medina1, Dimitra Tsivaka1,3
1Department of Neuroimaging, Institute of Psychology, Psychiatry & Neuroscience, King's College London, London, UK.
Human brain mapping
|February 10, 2024
概括
休息状态功能磁共振成像 (fMRI) 显示有组织的宫脊髓网络. 虽然可靠性是混合的,但它们的空间范围在不同会议中是一致的,这表明临床应用的潜力.
科学领域:
- 神经科学是一个神经科学.
- 功能神经成像 功能神经成像
- 脊髓研究研究 脊髓研究
背景情况:
- 休息状态功能磁共振成像 (fMRI) 已经确定了形成有组织的运动和感觉网络的内在脊髓活动.
- 评估脊柱fMRI的可靠性对于临床应用至关重要,因为它面临着独特的数据采集挑战.
研究的目的:
- 描述宫脊髓中的功能连接关系.
- 评估椎脊柱休息状态网络的会话间测试-重新测试可靠性.
主要方法:
- 从23名健康志愿者获得休息状态fMRI数据.
- 功能连接性估计使用种子-voxel地图和种子-种子相关性,种子在C5-C8灰质角.
- 使用类内相关系数和空间重叠的Dice系数来评估测试-重新测试的可靠性.
主要成果:
- 观察到明显的单侧背部 (感觉) 和腹部 (运动) 椎脊柱休息状态网络,主要局限于单个脊柱细分水平.
- 发现最强的相关性是在细分体内 - - ipsilateral 背腹连接.
- 测试-重新测试可靠性是混合的,语音可靠性很差,但对集群内的平均信号的可靠性更好,并且在会话之间网络的空间重叠很好.
结论:
- 椎脊柱休息状态网络在时间上表现出一致的空间表示,尽管混合测试-重新测试可靠性.
- 这些发现表明,脊柱fMRI网络在其空间范围上是可重现的,支持它们在临床研究中的潜在实用性.
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