使用超选择性Wada测试对患者语言侧面化的评估
Kazuo Kakinuma1, Shin-Ichiro Osawa2, Kazuto Katsuse3,4
1Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, 2-1 Seiryo, Aoba-ku, Sendai, 980-8575, Japan. kazuo.kakinuma.c1@tohoku.ac.jp.
Acta neurochirurgica
|February 10, 2024
概括
超选择性Wada测试 (ssWada) 准确地确定了患者的语言优势,成功率超过90%,副作用最小,比经典的Wada测试更好.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 的研究研究.
背景情况:
- 经典的Wada测试 (cWada) 识别了语言的主导地位,但具有10-30%的不良影响率.
- 这限制了对患者语言侧面化的准确评估.
研究的目的:
- 评估超选择性Wada测试 (ssWada) 对于确定语言优势的有效性.
- 评估ssWada在患者中的安全性和准确性.
主要方法:
- 对17名接受ssWada治疗的患者进行了回顾性分析.
- 麻醉剂注射到中脑动脉 (MCA) 的M1段,并进行对侧试验.
主要成果:
- 在95.5%的单方面M1注射试验中,ssWada正确地确定了语言的主导地位.
- 全球失语或完整的语言功能证实主导地位,报告的副作用很少.
结论:
- ssWada是一个非常有效的方法来确定语言占主导地位的半球.
- ssWada具有很高的成功率 (>90%) 和有利的副作用概况.
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