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Updated: Jul 3, 2025

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
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由DNA间隔器产生的染色质损伤导致RNA聚合酶II的降解

Jaime A Espinoza1, Dimitris C Kanellis1, Sheetanshu Saproo1

  • 1Science for Life Laboratory, Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 21 Stockholm, Sweden.

Nucleic acids research
|February 10, 2024
PubMed
概括

新的DNA间隔器通过破坏染色体稳定性和RNA聚合酶功能来杀死癌细胞而不会损害DNA. 这些化合物通过向基本细胞过程,为癌症治疗提供了一种新的方法.

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