个性化的格子结构假体作为下重建和假体修复的无移植解决方案:有限元分析
Guilherme Arthur Longhitano1, Murillo Chiarelli2, Daniel Prada3
1National Institute of Biofabrication (INCT-BIOFABRIS), Campinas, 13083-852, Brazil; Faculdade de Engenharia Química, Universidade Estadual de Campinas (UNICAMP), Campinas, 13083-852, Brazil; 3D Printing Open Lab, Center for Information Technology Renato Archer, Campinas, 13069-901, Brazil; Faculdade de Engenharia Mecânica, Universidade Estadual de Campinas (UNICAMP), Campinas, 13083-860, Brazil.
个性化的3D打印假肢显著减少重建下的压力,防止传统板块常见的疲劳骨折. 这项创新为大型缺陷提供了无移植解决方案,改善了患者的治疗结果.
科学领域:
- 生物材料工程是生物材料的工程.
- 医疗器械设计 医疗器械设计
- 整形外科手术 整形外科手术
背景情况:
- reconstruction对于口腔功能至关重要,但面临挑战,当前的方法,如板骨折和感染.
- 自生骨移植,在使用时,会导致捐赠者部位的发病.
- 现有的重建技术难以提供理想的长期解决方案.
研究的目的:
- 为了比较商业重建板的机械性能与个性化,格子结构的假肢.
- 在模拟生理负荷下评估应力分布和疲劳骨折的可能性.
- 评估一个无移植,3D打印解决方案的可行性,用于下重建.
主要方法:
- 用有限元分析 (FEA) 模拟咬伤和骨整合条件.
- 患者特定的医疗图像从一个有商业牌子骨折的患者得到了利用.
- 在商业板和个性化假肢之间比较了机械应力和应变分布.
主要成果:
- 与商业板相比,个性化的假肢表现出明显较低的最大·米塞斯等效应力,降低了疲劳骨折风险.
- 周围骨中的相当于·米塞斯菌株处于维护和重塑的生理范围之内.
- 格子结构的设计显示出卓越的机械稳定性.
结论:
- 个性化,增材制造的假肢为传统下重建板提供了一个有希望的替代方案.
- 这种方法可以防止疲劳失败,并消除对大缺陷的骨移植的需求.
- 设计方便直接整合牙假体,可能避免植入物.
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