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对于二次性上腺恶性病的上腺切除术后的术后结果
Rebecca L Green1, Terry P Gao1, Lindsay E Kuo1
1Department of General Surgery, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
The Journal of surgical research
|February 10, 2024
概括
对于二次上腺恶性瘤 (SM) 的上腺切除术,与良性上腺瘤相比,术后出血的风险增加. 患有MS的患者需要关于手术风险的仔细咨询.
科学领域:
- 手术瘤学手术瘤学
- 上腺腺细胞新生体
- 医学成果研究研究成果
背景情况:
- 上腺转移切除术的结果还没有得到很好的定义.
- 了解风险对于患者咨询至关重要.
- 上腺切除术用于恶性和良性疾病.
研究的目的:
- 为了比较二次上腺恶性瘤 (SM) 与良性非功能性 (BNF) 上腺瘤的上腺切除术的结果.
- 为了确定与MS的上腺切除术相关的特定风险.
- 为了告知病人咨询上腺转移切除术.
主要方法:
- 利用了2015-2020年国家外科手术质量改进计划数据.
- 鉴定了为SM和BNF瘤进行上腺切除术的患者.
- 排除了其他并发手术的患者.
- 使用多变量逻辑回归来比较人口统计,并发病,外科手术期间的因素和结果.
主要成果:
- 332名患者患有MS,3164人患有BNF新生体.
- 肌痛性脊髓炎患者年龄较大,并患有更多的并发病 (COPD,类固醇使用,出血障碍).
- 在死亡率,发病率,重新手术,再入院或非家庭出院方面没有显著差异.
- 在SM组中,术后出血率明显较高 (6.3%对2.6%,P<0.001).
- 经过多变量分析 (OR 2.34),MS出血风险的增加仍然存在.
结论:
- 对于MS的上腺切除与手术后出血的风险高于BNF瘤的风险.
- 由于MS而接受上腺切除术的患者需要对出血风险进行适当的咨询.
- 这项研究突出了在上腺转移切除决策中需要考虑的特定并发症.
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