查工具用于检测临床无声心脏沙尔科毒症
Alessandro De Bortoli1, Kristin A Dawson2, Dalia Hashem3
1Department of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada; Department of Cardiology, Vestfold Hospital Trust, Tønsberg, Norway.
Respiratory medicine
|February 10, 2024
概括
临床无声性心脏沙尔科毒症 (CS) 影响超过22%的心脏外沙尔科毒症患者. 结合像霍尔特和信号平均心电图 (SAECG) 这样的测试,可以提高CS的查准确度.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 免疫学 免疫学 免疫学
背景情况:
- 临床无声性心脏类瘤 (CS) 存在风险,需要对心脏外类瘤患者进行查.
- 对CS的最佳查策略仍未确定.
- 早期发现CS对于管理不良结果至关重要.
研究的目的:
- 评估各种查工具的诊断产量,以诊断临床无声性心脏沙尔科毒症 (CS) 在心脏外沙尔科毒症患者.
- 为了确定这个人群中CS的患病率和显著的心脏参与.
- 评估组合查测试与单个模式的有效性.
主要方法:
- 未来包括患有心脏外沙尔科毒性病的患者.
- 查包括症状史,心电图,心声图,霍尔特和SAECG.
- 用晚期加多增强 (LGE) 的心磁共振 (CMR) 作为CS诊断的黄金标准.
主要成果:
- 在22.5%的患者中诊断出临床无声的CS;在14.7%的患者中诊断出显著的心脏参与.
- 高血压与CS有很强的关联 (p < 0.05).
- 组合的霍尔特和SAECG显示出高负预测值 (91.7%),表现优于单个测试.
结论:
- 临床上沉默的CS和显著的心脏参与在心脏外样症患者中很普遍.
- 与高血压的关联值得考虑,以避免误诊.
- 像Holter和SAECG这样的可访问的查工具可以帮助识别不需要进一步CMR调查的患者.
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