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Updated: Jul 3, 2025

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CircSTRBP通过通过招募IGF2BP1的IGF2BP1通过增加NOX4mRNA稳定性来促进H2O诱导的镜片表皮细胞功能障碍

Di Li1, Xuanyi Che1, Ningning Gao1

  • 1Department of Ophthalmology, Shaanxi Provincial People's Hospital, Xi'an, China.

Experimental eye research
|February 10, 2024
PubMed
概括

循环RNA circSTRBP通过增加镜片上皮细胞中的氧化应激和亡来促进与年龄相关的白内障. 它通过类似胰岛素的生长因子2mRNA结合蛋白1 (IGF2BP1) 增强尼古丁胺氨酸二核酸氧化酶亚单元4 (NOX4) 的稳定性.

关键词:
与年龄相关的白内障在IGF2BP1中.镜片上皮细胞是镜片上皮的细胞.在NOX4中,NOX4是氧化应激是一种氧化应激.环绕STRBPBP的时间

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