野生吉本 (Hoolock tianxing) 肠道菌群的生态进化动态,季节性饮食变化
Shao-Ming Gao1, Han-Lan Fei1,2, Qi Li1
1School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, PR China.
Nature communications
|February 10, 2024
概括
野生的吉本,就是野生的吉本.
科学领域:
- 微生物生态学 微生物生态学
- 病毒学 病毒学
- 动物生态动物生态学
背景情况:
- 肠道微生物组帮助动物适应饮食变化.
- 肠道菌群对野生动物饮食变化的反应是未知的.
研究的目的:
- 为了研究野生吉本 (Hoolock tianxing) 肠道菌体的生态进化动态,以应对季节性饮食变化.
主要方法:
- 在15个月内收集了6只吉本的便样本和食数据.
- 利用病毒和微生物转基因组学来识别菌体基因组.
- 分析了菌体种群动态和功能基因配置文件.
主要成果:
- 确定了39,198个毒性和温和菌体基因组.
- 在菌体种群中观察到的季节性波动与饮食变化相关 (高水果与高叶).
- 在高叶季节观察到针对Lachnospiraceae的毒性菌体增加和与Bacteroidaceae宿主的温带菌体减少.
- 通过横向基因转移在温带菌体中发现了毒素-抗毒素基因的丰富.
- 在毒性和温和菌体中为特定基因选择的同进化过程.
结论:
- 吉肠菌群的组成和功能随着饮食的季节性变化而变化.
- 菌体与宿主之间的相互作用是复杂的,并受到同进化的压力的影响.
- 肠道菌群-微生物群的相互作用对于子适应饮食变异至关重要.
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