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Updated: Jul 3, 2025

Identification of Key Factors Regulating Self-renewal and Differentiation in EML Hematopoietic Precursor Cells by RNA-sequencing Analysis
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Published on: November 11, 2014

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由LIN28A非法定功能的影响下,动态核细胞相分离指示多能干细胞命运决定

Tianyu Tan1,2, Bo Gao3, Hua Yu1

  • 1Center for Stem Cell and Regenerative Medicine, Department of Basic Medical Sciences, and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.

Nature communications
|February 10, 2024
PubMed
概括

LIN28A蛋白在细胞核中形成相分离的凝聚物,在多能转换过程中调节细胞命运决策. 这突出了LIN28A在核功能和细胞重编程中的新,RNA独立的作用.

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