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在染色体尺度上,Lepus oiostolus (Lepus,Leporidae) 的基因组组合

Shuo Feng¹, Yaying Zhang², Zhaotong He²

¹State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining, 810016, China. fengshuo8894@126.com.

Scientific data

|February 10, 2024

概括

我们向您介绍了首个染色体规模的基因组组件Lepus oiostolus,一种来自青海-西藏高原的物种. 这种高质量的基因组为研究类动物进化和遗传学提供了至关重要的资源.

科学领域:

基因组学就是基因组学.
进化生物学进化生物学
哺乳动物遗传学哺乳动物遗传学

背景情况:

(L. oiostolus) 是青海-西藏高原的特有物种.
遗传研究受到缺乏L. oiostolus.参考基因组的阻碍.

研究的目的:

报告L. oiostolus. 的高质量的染色体规模基因组组合.
提供一个有价值的基因组资源,用于未来的研究Leporidae进化.

主要方法:

高质量的基因组组装使用先进的测序技术.
脚手架固定在24个染色体上.
基因组注释以识别蛋白质编码基因和可转移元素.

主要成果:

总组装的基因组长度为2.80Gb,连续N50长度为64.25Mb.
鉴定了22295个编码蛋白质的基因.
发现49.84%的基因组由可转移的元素组成,其中很大一部分是长间隔核元素 (LINE).

结论:

这项研究报告了L. oiostolus. 的第一个染色体规模基因组组合.
该基因组作为一个基础资源,用于调查Leporidae家族内的进化历史和遗传多样性.

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