术前老年营养风险指数是预测患有退行性腰部疾病的老年患者中术后妄想的有用因素
概括
较低的老年人营养风险指数 (GNRI) 与老年患者在转腰椎体间融合 (TLIF) 后后术后 Delirium (POD) 的风险增加有关. 术前GNRI评估可以帮助预测这一群体的POD风险.
科学领域:
- 老年医学 老年医学
- 神经外科 神经外科
- 营养科学 营养科学
背景情况:
- 手术后痴呆症 (POD) 是接受脊髓手术的老年患者的常见并发症.
- 跨腰部体融合 (TLIF) 是一种经常用于退行性腰部疾病的手术.
- 老年患者TLIF后POD的预测标记对于风险分层和管理至关重要.
研究的目的:
- 调查老年营养风险指数 (GNRI) 对手术后痴呆症 (POD) 在接受TLIF的老年患者的预测价值.
- 建立GNRI作为一种潜在的查工具,用于识别TLIF后POD风险较高的患者.
主要方法:
- 在2016年至2022年期间接受TLIF的324名老年患者的回顾性分析.
- 使用基于术后医疗记录的混评估方法诊断POD.
- 使用血清白蛋白和体重计算手术前的GNRI.
- 多变量后勤回归和接收器操作特征 (ROC) 曲线分析,以评估GNRI和POD之间的关联.
主要成果:
- 在50名患者 (15.4%) 中发生POD.
- 患有POD的患者与没有妄想的患者相比,平均GNRI显著降低.
- 低GNRI是TLIF后POD的独立预测因子 (OR 0.714,p=0.018).
- 预测POD的最佳GNRI截止值为96.370 (AUC为0.738).
结论:
- 在老年患者中,较低的手术前GNRI与TLIF后POD风险增加显著相关.
- 术前GNRI评估是预测POD风险的有价值和有效的工具.
- 将GNRI查整合到手术前评估中可能会改善患者的治疗结果,并减少POD发生率.
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