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Updated: Jul 3, 2025

Examination of Proteins Bound to Nascent DNA in Mammalian Cells Using BrdU-ChIP-Slot-Western Technique
09:14

Examination of Proteins Bound to Nascent DNA in Mammalian Cells Using BrdU-ChIP-Slot-Western Technique

Published on: January 14, 2016

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SIN3A 基因素脱乙酶的作用抵消了 MUS81 的作用,促进了停滞的叉子稳定性

Sergio Muñoz1, Sonia Barroso1, Nibal Badra-Fajardo1

  • 1Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, 41092 Seville, Spain; Departamento de Genética, Facultad de Biología, Universidad de Sevilla, 41012 Seville, Spain.

Cell reports
|February 11, 2024
PubMed
概括

SIN3A复合体通过在停滞的复制分叉 (RFs) 中去乙化基因组来保护基因组稳定性,防止DNA断裂,并在压力下促进复制重启.

关键词:
科普:分子生物学 分子生物学美国81美元.这是一个SIN3A复合体.基因素脱乙化 基因素脱乙化复制子复制子复制压力是复制的压力.

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