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Updated: Jul 3, 2025

Mass Spectrometric Approaches to Study Protein Structure and Interactions in Lyophilized Powders
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在制药工艺开发过程中,拉曼光谱的应用,用于确定蛋白A染色学中的关键质量属性

Jingyi Chen1, Jiarui Wang2, Rudger Hess2

  • 1Boehringer Ingelheim Pharma GmbH / Co. KG, Biberach an der Riss, Germany; Institute of Functional Interfaces, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen 76344, Germany.

Journal of chromatography. A
|February 11, 2024
PubMed
概括

拉曼光谱,一个过程分析技术 (PAT),有效地监测蛋白质A染色体中的关键质量属性 (CQAs). 这加速了生物工艺的开发,并使实时释放制造成为可能.

关键词:
在线监控在线监控机器学习 机器学习过程分析技术 过程分析技术过程稳固性 过程稳固性治疗性抗体治疗性抗体

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