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首次描述了一只狗的初级食道囊细胞肉瘤

Anelise Bonilla Trindade-Gerardi¹, Camila Alves da Silveira², Janyni Duz³

¹Department of Animal Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.

Topics in companion animal medicine

|February 11, 2024

概括

这项研究报告了第一例患有初级食道囊细胞肉瘤的狗病例,这是一种罕见的癌症,在11岁的犬中死后诊断出咳和吐的罕见癌症. 这种侵袭性瘤导致了致命的吸附性肺炎和败血症.

科学领域:

兽医病理学兽医病理学
在瘤学瘤学.
狗医疗狗医疗狗医疗

背景情况:

食道瘤在狗中并不常见.
囊性肉瘤是一种罕见且具有攻击性的恶性瘤,在兽医文献中数据有限.

研究的目的:

报告了第一例被证实的一只狗中原发性食道囊细胞肉瘤的病例.
描述这种罕见的食道瘤的临床,诊断和组织病理发现.

主要方法:

临床案例介绍,一个11岁的犬患有慢性咳和吐.
诊断成像 (放射学,内镜) 和组织病理学分析,包括免疫组织化学.
尸检检查以确定瘤的范围和转移.

主要成果:

内镜检查显示了大量的侵袭性食道质量,导致显著的膜阻塞.
组织病理学和免疫组织化学证实了差异化,高等级 (Ki-67 ~30%) 囊细胞肉瘤.
瘤转移到肺部和脏,狗死于吸入性肺炎和败血症.

结论:

这一病例代表了首次描述狗中原发性食道囊细胞肉瘤的情况.
早期识别和诊断对于潜在的未来病例至关重要,尽管这种瘤看起来非常具有攻击性.
需要进一步的研究,以了解狗食道囊性肉瘤的生物学和潜在治疗方法.

关键词:

狗类犬类动物狗类犬类消化道中的食道.组织细胞瘤瘤.发生转移的转移.肉瘤肉瘤是一种肉瘤.

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