治疗耐药性抑郁症:白种人和少数民族个人之间的访问,途径和结果的比较研究
Shanaya Rathod1, Zuzanna Skórniewska2, Tomas Engelthaler2
1Research and Innovation Department, Southern Health NHS Foundation Trust, Southampton SO30 3JB, UK.
Journal of affective disorders
|February 11, 2024
概括
治疗耐药性抑郁症 (TRD) 护理途径在英国的各个族群之间存在显著差异. 白人患者接受的抗抑郁药处方比少数民族患者更多,突出了需要进一步调查和有针对性的干预措施的潜在临床偏见.
科学领域:
- 精神病学是一个精神病学.
- 临床药理学 临床药理学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 治疗耐药性抑郁症 (TRD) 被定义为对至少两种抗抑郁药物治疗缺乏反应.
- 了解TRD患者的个人资料对于优化心理健康护理至关重要.
- 心理健康治疗中的种族差异需要彻底调查.
研究的目的:
- 用电子健康记录分析TRD患者的临床特征.
- 将少数民族的治疗途径和治疗结果与英国非少数民族TRD患者进行比较.
主要方法:
- 一个追溯的,纵向的,观察性队列研究.
- 通过CRIS系统利用了来自10个英国心理健康NHS信托机构的1048名TRD患者的非身份化数据.
- 分析了匿名的电子医疗记录.
主要成果:
- 20.2%的TRD患者被确定为BAME,79.8%被确定为白色.
- 白人患者的抗抑郁药处方比BAME患者多 (p < 0.001).
- 在族群之间观察到治疗模式和并发症的显著差异.
结论:
- 基于种族,TRD患者的护理途径存在显著差异.
- 需要进一步的研究来确定这些临床偏差的原因.
- 提高认识和教育对于确保对少数民族人口提供公平有效的TRD待遇至关重要.
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