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Updated: Jul 3, 2025

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers
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在哺乳动物细胞表达的治疗性蛋白候选物中停止-Codon阅读

Zhongqi Zhang1, Neelam Khanal1, Andrew B Dykstra1

  • 1Process Development, Amgen Inc. Thousand Oaks, CA 91320, USA.

Journal of pharmaceutical sciences
|February 11, 2024
PubMed
概括

在治疗性蛋白质中,停止密码子读透是常见的,影响产品质量. 优化在停止密码子附近的DNA序列和监测读透对于生物制药开发至关重要.

关键词:
质谱测量质量谱测量阅读通过阅读.停止 codon 的使用.翻译中的错误

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