围产期抑郁症和婴幼儿神经发育:一个系统性审查和元分析
Xiaoxiao Fan1, Ni Wu1, Yiming Tu1
1Wuhan University School of Nursing, Wuhan University, 169 Donghu Road, Wuhan 430071, China.
Neuroscience and biobehavioral reviews
|February 11, 2024
概括
围产期抑郁会对婴儿和幼儿的神经发育产生负面影响,影响认知,语言和运动技能. 产前抑郁症与早期儿童发育迟缓的相关性更强.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 公共卫生 公共卫生
背景情况:
- 关于围产期抑郁症对婴幼儿神经发育的影响的研究有限.
- 现有研究表明,关于这一关键发育时期的结果不一致.
研究的目的:
- 系统地审查和元分析婴幼儿中围产期抑郁症和神经发育之间的关联.
- 调查抑郁症时间 (产前与产后) 和测量方法对神经发育结果的影响.
主要方法:
- 对23项研究进行了系统审查和元分析.
- 包括评估神经发育在出生后前两年的研究.
- 对认知,语言和运动发育结果的分析.
主要成果:
- 围产期抑郁症与较差的认知 (d = -0.19),语言 (d = -0.24) 和运动 (d = -0.15) 发育有关.
- 产前抑郁症与认知,语言和运动延迟有显著的关联.
- 产后抑郁症与这些延迟的关联在统计学上并不显著.
结论:
- 围产期是后代神经发育的一个敏感窗口.
- 对于优化儿童发育结果,对母亲产前抑郁症的早期识别和干预至关重要.
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