死亡癌症患者的腹腔补水:国家注册研究
Lisa Martinsson1, Peter Strang2, Staffan Lundström2
1Department of Radiation Sciences, Oncology (L.M.), Umeå University, Umeå, Sweden.
Journal of pain and symptom management
|February 11, 2024
概括
在生命末期癌症护理中,肠道补水与呼吸困难增加有关. 这种水分更常见于年轻的男性,那些患有特定癌症的人,以及在急性医院环境中.
科学领域:
- 抚慰性护理是一种缓解性护理.
- 在瘤学瘤学.
- 临床水化 临床水化
背景情况:
- 癌症患者生命末期临床辅助水分是有争议的,缺乏强有力的证据.
- 在临床环境和国家之间,生命终端水合的实践有很大差异.
研究的目的:
- 为了研究特定症状 (气喘,呼吸道分泌物,混乱) 与在终身癌症护理中进行腹腔补水的管理之间的相关性.
- 在分析中调整人口统计因素 (性别,年龄) 和死亡地点.
主要方法:
- 使用了瑞典息治疗注册表 (2011-2021) 的数据.
- 包括在医院,住院护理或专门的息治疗机构死亡的成年癌症患者.
- 采用千平方测试和逻辑回归来分析亲肠道水分和症状之间的关联.
主要成果:
- 在年轻的患者,男性和急性病患者 (p < 0.001) 中,腹腔补水更频繁.
- 血液性恶性瘤 (20%) 和卵巢癌 (16%) 的水合率较高,而脑瘤的水合率较低 (6%).
- 气喘,呼吸道分泌物和混乱都与腹腔灌水相关 (p < 0.001);然而,在调整后,只有气喘仍然显著 (OR 1.56).
结论:
- 在接近生命终点的癌症患者中,亲肠补水和增加呼吸困难之间存在关联.
- 肠道补水在年轻男性,患有血液性恶性瘤或卵巢癌的患者以及急性医院环境中更为普遍.
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