在老年成人癌症幸存者中进行简短的行为激活随机对照试验的协议
Rebecca M Saracino1, Ellen Y Park1, Caraline Demirjian1
1Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 633 Third Avenue, 4(th) Floor, New York, NY 10017, USA.
Journal of geriatric oncology
|February 11, 2024
概括
行为激活 (BA) 正在测试,作为对老年癌症幸存者的抑郁症的电话交付干预. 本试点研究旨在评估其可行性和初步有效性,以改善情绪和活动水平.
科学领域:
- 老年精神病学是一门精神病学专业.
- 在瘤学瘤学.
- 心理治疗研究 心理治疗研究
背景情况:
- 高达35%的老年癌症幸存者 (OACS) 经历了严重的抑郁.
- 由于疲劳,认知障碍和并发症,OACS易患抑郁症.
- 行为激活 (BA) 是一种经过验证的抑郁症治疗方法,具有OACS的潜力.
研究的目的:
- 通过电话和视频会议进行的适应OACS (BBA-OACS) 的简短BA干预措施的有效性.
- 评估与支持性心理治疗 (SP) 相比,BBA-OACS的实施结果 (可接受性,可行性,忠实性).
- 确定BBA-OACS对抑郁症状,焦虑,应对和活动水平的初步影响.
主要方法:
- 纪念斯隆凯特林癌症中心的一项试点随机对照试验 (RCT).
- 参与者被随机分配到每周10次BBA-OACS或SP的会议中.
- 将招募70名报告抑郁症状的OACS,并在干预前后进行评估.
主要成果:
- 这个部分不在所提供的摘要中.
- 这个部分不在所提供的摘要中.
- 这个部分不在所提供的摘要中.
结论:
- 如果成功,BBA-OACS可以为OACS提供一种可访问的,基于证据的治疗方法.
- 需要进一步的研究来证实BA在更大的试验中的有效性.
- 这种干预有可能改善OACS患者的抑郁症和其他健康结果.
相关概念视频
01:21Cancer Survival Analysis
346
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
346
01:13Randomized Experiments
6.9K
The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Simple randomization
Simple...
6.9K
01:11Blinding
2.4K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
2.4K