儿科患者复发性急性乳腺炎的危险因素:基于注册表的队列研究
Yotam Aharon Shiner1,2, Orit Samuel3,4,5, Walid Saliba4,5
1Department of Otolaryngology, Head and Neck Surgery, Lady Davis Carmel Medical Center, Haifa, Israel. yotamsh@clalit.org.il.
概括
儿童的重复性急性乳腺炎与乳腺切除术和乳腺炎在最初的发作期间的胀有关. 乳腺切除术是复发性急性乳腺炎的主要独立风险因素.
科学领域:
- 儿科耳鼻喉科 儿科耳鼻喉科
- 传染性疾病 传染性疾病
背景情况:
- 急性乳腺炎是乳腺骨的严重细菌感染.
- 急性乳腺炎的复发在儿科管理中提出了独特的挑战.
- 确定复发的风险因素对于有效的治疗策略至关重要.
研究的目的:
- 描述患有复发性急性乳腺炎的儿科患者.
- 确定与儿童复发性急性乳腺炎相关的重大风险因素.
主要方法:
- 一项回顾性队列研究,利用来自以色列大型卫生维护组织的电子病历.
- 在2008-2018年期间住院的儿童中发现和验证了急性乳腺炎的病例.
- 将复发性乳腺炎患者的特征与初始队列进行比较,以确定风险因素.
主要成果:
- 确定了1115例急性乳腺炎病例;5.1% (57/1115) 经历了复发.
- 复发病例主要影响24个月以下的儿童 (73.4%).
- 第一次发作期间的乳腺切除术 (HR=4.7) 和乳腺胀 (HR=2.55) 是显著的风险因素;乳腺切除术是多变量分析中唯一的独立预测因素.
结论:
- 乳腺切除术是儿童复发性急性乳腺炎的重要独立风险因素.
- 在最初的发作期间,乳腺区域的胀也增加了复发的风险.
- 这些发现强调了在治疗急性乳腺炎时考虑手术史和初始呈现的重要性,以防止复发.
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