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在精神分裂症患者的唾液列丁3水平

Saba Shoukat^1,2, Humaira Fayyaz Khan^1,2, Muhammad Kashif

¹Islamic International Medical College, Rawalpindi, Pakistan.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

|February 11, 2024

概括

与健康个体相比,精神分裂症患者的唾液胆-3水平显著更高. 这一发现表明唾液 galectin-3 可能作为一个有用的生物标志物来诊断精神分裂症.

科学领域:

生物化学生化学
精神病学是一个精神病学.
医学诊断医学诊断医学诊断

背景情况:

盖列-3与炎症过程有关.
精神分裂症是一种复杂的精神疾病,具有潜在的炎症基础.
研究精神分裂症的生物标志物对于早期诊断和管理至关重要.

研究的目的:

为了比较精神分裂症患者和健康对照者的血清和唾液胆-3水平.
在精神分裂症中探索唾液和血清胆-3之间的相关性.
评估唾液中甲-3作为精神分裂症诊断指标的潜力.

主要方法:

一项涉及30名精神分裂症患者和30名健康对照者的横截面研究.
收集了唾液和血清样本.
与酶相关的免疫吸收试验 (ELISA) 用于测量加勒-3水平.
统计分析包括独立样本的t测试和皮尔森相关性.

主要成果:

在精神分裂症患者中,唾液中的平均加勒-3水平显著升高 (p < 0.001).
在精神分裂症患者的唾液和血清胆-3水平之间发现了显著的积极关联 (p = 0.03).

结论:

在精神分裂症中,唾液中甲-3水平升高.
在精神分裂症患者中,唾液和血清胆素-3水平具有积极的相关性.
唾液甲-3显示出作为精神分裂症诊断生物标志物的潜力.

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