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通过三维表面接种的聚乙烯染抗病毒) - - 基化) - - 基化) - - 基化)

Rie Hirao¹, Hisato Takeuchi¹, Jumpei Kawada¹

¹Toyota Central R&D Labs, Inc., Nagakute, Aichi 480-1192, Japan.

ACS applied materials & interfaces

|February 12, 2024

概括

研究人员使用四级化合物 (QAC) 为聚烯开发了一种耐用的抗病毒涂层. 这种功能化塑料有效地抑制病毒感染,并且耐受伤和磨损,扩大了生物杀菌表面的应用.

科学领域:

材料科学材料科学材料科学
聚合物化学聚合物化学
表面工程是什么?表面工程是什么?
抗病毒技术的使用.

背景情况:

聚烯 (PP) 需要生物杀菌特性来抑制病毒,但其表面能量较低,阻碍了分子相互作用.
四级化合物 (QAC) 具有生物杀伤性作用,导致带有表面结合四级 (QA) 的PP纤维.
现有质量保证涂料的耐用性对抗诸如划伤和磨损之类的物理磨损仍然是一个挑战.

研究的目的:

开发一种创建耐用,抗病毒功能化的聚烯表面的方法.
调查涂层厚度和QACs对抗病毒疗效和耐久性的影响.
探索这种方法对其他低表面能量聚合物的潜在应用.

主要方法:

通过移植聚合和化,使聚烯与聚 (N--4-乙烯基化) (PBVP) 功能化.
使用紫外线照射参数控制PBVP涂层厚度,表面粗度和QAQ密度.
使用与包裹模型病毒 (细菌 φ6) 的斑块测试进行抗病毒疗效评估.

主要成果:

可调节的紫外线照射持续时间和强度允许控制涂层厚度,粗度和QAC负载.
优化的PBVP涂层PP样本在60分钟内将病毒标位降低了约5个日志.
在模拟和磨损后,抗病毒活性保持不变,这表明强大的QAC集成.

结论:

成功开发了一种快速创建耐用,抗病毒功能化的聚烯表面的方法.
涂层的有效性和耐用性与受控的QAC负载和厚度有关.
这种方法适用于各种olefinic聚合物,使生物杀菌表面的广泛使用成为可能.

关键词:

这是一种抗病毒药物.同价键是一种共价键.植入物聚合物化的植入物聚合物聚烯聚烯的使用方法四级化合物四级化合物

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