临床依恋丧失与没有糖尿病的成年人中葡萄糖升高的横截面相关
Hamdi S Adam1, Rebecca Molinsky1, Bruno Bohn1,2
1Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Journal of clinical periodontology
|February 12, 2024
概括
牙周关节损失等牙周关节指标与非糖尿病成年人中更高的禁食葡萄糖和糖尿病前期风险有关. 牙疾病指标也与胰岛素耐药性增加相关,这表明口腔健康和心脏代谢健康之间存在联系.
科学领域:
- 口腔健康 口腔健康
- 心脏代谢健康的健康状况
- 内分泌学 在内分泌学.
背景情况:
- 牙周病是一种常见的炎症性疾病.
- 新出现的证据表明牙周病与糖尿病等全身性疾病之间存在联系.
- 年轻的非糖尿病成年人可能是研究这些关联的早期窗口.
研究的目的:
- 为了调查牙周测量和糖尿病前期之间的横截面关联.
- 研究非糖尿病成年人的牙周测量和心脏代谢生物标志物之间的关系.
- 为了区分近距离与全口腔牙周测量措施之间的影响.
主要方法:
- 从口腔感染,葡萄糖不耐受和胰岛素抵抗研究中分析了1071名非糖尿病参与者 (平均年龄32.2岁).
- 牙周的测量包括近距离临床附着损失 (i-CAL) 和探测深度 (i-PD).
- 糖尿病前期和心脏代谢生物标志物 (葡萄糖,HbA1c,胰岛素,HOMA-IR) 通过临床检查和禁食血液测试进行评估,并进行回归分析.
主要成果:
- 糖尿病前期的患病率为12.5%.
- 较高的i-CAL与高的禁食葡萄糖和糖尿病前期的几率增加有显著的关联.
- 增加的近距离探测深度 (i-PD) 与更高的胰岛素抵抗 (HOMA-IR) 相相关.
结论:
- 临床的近距离连接损失与年轻成年人的快餐葡萄糖和糖尿病前期的升高有关.
- 中近距离探测深度与胰岛素抵抗有关.
- 需要进一步的研究来探索牙周病与糖尿病前期发展之间的联系.
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