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相关概念视频

Menopause01:28

Menopause

165
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
165
Obesity01:24

Obesity

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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
503
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

389
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
389
Signs of Puberty01:27

Signs of Puberty

350
Puberty is a critical phase, typically beginning between the ages of 8 and 13 in girls and 9 and 14 in boys, though timing can vary based on genetics, environmental factors, and overall health. This period is characterized by the development of secondary sexual characteristics and the attainment of reproductive potential. Endocrine changes underpin puberty, with hormonal surges of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) instigated by Gonadotropin-Releasing Hormone (GnRH)...
350
Bone Disorders01:29

Bone Disorders

3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Stress Prevention and Stress Management Techniques IV01:26

Stress Prevention and Stress Management Techniques IV

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Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
29

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A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice
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肥胖和更年期的情况.

Santiago Palacios1, Peter Chedraui2, Rafael Sánchez-Borrego3

  • 1Palacios's Clinic for Women's Health, Madrid, Spain.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
|February 12, 2024
PubMed
概括

肥胖是一种复杂的疾病,而不是缺乏意志力. 对于更年期妇女来说,肥胖会使健康状况恶化,但某些激素疗法可能是安全的,这取决于类型和分娩.

关键词:
肥胖问题 肥胖问题骨折的风险 骨折的风险激素疗法激素疗法是一种激素疗法.更年期 绝经 更年期血管运动的症状.

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科学领域:

  • 生殖内分泌学和新陈代谢.
  • 妇女健康与老龄化问题

背景情况:

  • 肥胖是一种多因素的慢性疾病,而不是意志力的问题.
  • 更年期涉及荷尔蒙和身体组成的变化,增加内脏脂肪和健康风险.
  • 肥胖会影响生殖荷尔蒙,并与月经不规律和更年期症状加剧有关.

研究的目的:

  • 为了澄清肥胖,衰老,更年期和荷尔蒙水平之间的复杂相互作用.
  • 评估更年期激素治疗 (MHT) 对肥胖女性的风险.

主要方法:

  • 关于肥胖,更年期和激素治疗的现有文献的综述.
  • 在肥胖妇女中与MHT相关的血栓栓塞性疾病的风险因素分析.

主要成果:

  • 肥胖会在更年期期间加剧心脏代谢,机械和心理健康问题.
  • 肥胖与月经周期的改变,发热,睡眠障碍,疼痛和生活质量的降低有关.
  • 透皮雌激素单独或组合MHT不会提高肥胖女性的血栓形成风险.

结论:

  • 肥胖严重影响中年和更年期妇女的健康.
  • 肥胖妇女使用MHT时发生血栓栓塞事件的风险取决于MHT的类型和施用途径.
  • 透皮MHT为肥胖女性的更年期症状管理提供了更安全的替代方案.