在国家健康和营养检查调查中,抑郁症和糖尿病视网膜病变之间的关联,2011年至2018年
Praneeth Kalva1, Aaron Shi1, Akash Kakkilaya1
1Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
概括
患有糖尿病视网膜病变 (DR) 的人群中,抑郁症比单独患有糖尿病 (DM) 更常见. 然而,这种关联可能受到其他健康状况的影响,需要进一步调查抑郁症和DR之间的联系.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 精神病学是一个精神病学.
背景情况:
- 糖尿病视网膜病变 (DR) 是糖尿病患者视力丧失的主要原因.
- 抑郁症和DR之间的联系还不太清楚,现有研究有限.
- 现有研究往往受到小样本大小和单中心数据的影响.
研究的目的:
- 调查DR患者中抑郁症的患病率.
- 在一个大型的国家队列中检查抑郁症和DR之间的关联.
- 探索抑郁症和DR之间的关系中的潜在调解因素.
主要方法:
- 追溯性,横截面的研究设计.
- 利用了2011年至2018年国家健康和营养检查调查 (NHANES) 的数据.
- 包括DM参与者的人口,医疗和检查数据,进行加权和多变量分析.
主要成果:
- 该研究包括22,618名参与者,DM流行率为13.9%,DR为2.9%.
- 抑郁症的患病率在DR组 (19.3%) 与仅DM组 (14.2%) 相比更高.
- 在调整了并发症后,DR和抑郁症之间的显著关联消失了;然而,抑郁症与自我感知的健康状况较差相关.
结论:
- 抑郁症在患有糖尿病视网膜病变的个体中比仅患有糖尿病的人更为普遍.
- 抑郁症和DR之间观察到的关系可能受到其他同时存在的疾病的影响.
- 需要进一步的研究来阐明抑郁症,糖尿病视网膜病变和并发症之间的复杂相互作用.
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