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在Fontan之后的延长性肺输液中对手术前的西尔德纳菲尔进行了回顾性研究
Dicky Fakhri1, Pribadi Wiranda Busro1, Budi Rahmat1
1Department of Surgery, Pediatric and Congenital Heart Surgery Unit, National Cardiovascular Center Harapan Kita, West Jakarta, Indonesia.
Annals of pediatric cardiology
|February 12, 2024
概括
在手术前使用西尔代纳菲尔可能会减少Fontan手术后的延长性肺溢液. 这项研究发现,在手术前至少六个月使用西尔德纳菲尔的患者中,风险较低.
科学领域:
- 心脏病学 心脏病学
- 儿科手术 儿科手术
背景情况:
- 芬坦手术是复杂的先天性心脏病的缓解手术.
- 长时间的多流是术后的一个严重并发症.
- 该中心10%的患者在2017年至2021年期间经过Fontan手术后出现了延长的肺流.
研究的目的:
- 调查手术前使用西尔代纳菲尔在预防Fontan手术后延长的多流液中的作用.
主要方法:
- 分析了一组158名接受Fontan手术的患者.
- 患者根据长期流的发展被分为几组.
- 在手术前使用西尔代纳菲尔 (≥6个月) 被评估为风险因素.
主要成果:
- 17名患者出现了长时间的肺溢,而141名患者没有.
- 在手术前使用西尔代纳菲尔的患者表现出长期多流的风险显著降低 (OR:0.32,P=0.027).
结论:
- 在手术前至少六个月服用西尔代纳菲尔可能会降低Fontan手术后延长的多流的发生率.
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