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Updated: Jul 3, 2025

Real Time Detection of In Vitro Tumor Cell Apoptosis Induced by CD8+ T Cells to Study Immune Suppressive Functions of Tumor-infiltrating Myeloid Cells
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阻断EP2和EP4可以防止人体单细胞骨髓原体衍生抑制细胞中瘤诱导的抑制特征

Jorge Cuenca-Escalona1, Beatriz Subtil1, Alba Garcia-Perez1

  • 1Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, Netherlands.

Frontiers in immunology
|February 12, 2024
PubMed
概括

瘤衍生的前列腺素E2 (PGE2) 通过EP2/4受体促进免疫抑制的髓质衍生抑制细胞 (MDSCs). 阻止这些受体可以防止MDSC诱导的免疫抑制,从而成为潜在的癌症治疗点.

关键词:
乙质前列腺受体2型受体电子性质素受体4型受体在M-MDSCs.的前列腺素E2的前列腺素E2.瘤微环境是一个微环境.

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