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帕拉西托醇手术内给药时间对术后发的影响:一项随机双盲对照试验

Medha Mohta¹, T Bindu Mounika¹, Asha Tyagi¹

¹Department of Anaesthesiology and Critical Care, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.

Indian journal of anaesthesia

|February 12, 2024

概括

在手术后期服用 (PCM) 会减少发和低温. 这种时间比早期给药或没有PCM对患者的康复更有效.

科学领域:

麻醉学麻醉学
药理学药理学是指药理学的学科.
手术患者护理手术患者护理

背景情况:

降醇 (PCM) 具有抗的特性,但可能会增加手术期间低温的风险.
为了减轻发和低温症,PCM的最佳时间尚未确立.

研究的目的:

为了比较IVPCM在不同手术时间点接受IVPCM的患者中发和术后低温的发生率.
评估PCM时间对术后止痛药需求的影响.

主要方法:

一项随机研究,涉及225名成人患者,在全身麻醉下接受选择性手术.
三组:早期PCM (诱导后),晚期PCM (手术结束前30分钟),和控制 (没有PCM).
静脉注射PCM (15 mg/kg,最大1g) 和吗啡 (0.1 mg/kg) 进行了. 统计分析包括千平方和ANOVA.

主要成果:

与早期PCM (29.3%) 和对照 (30.6%) 组相比,晚期PCM组的发发病率显著降低 (12%).
在晚期PCM组与早期PCM组和对照组相比,术后低温的发生率显著降低.
晚期PCM组的患者在术后需要更少的止痛药,在第一次止痛剂剂量之前的时间更长.

结论:

在手术完成前30分钟输入静脉PCM有效减少术后发和低温.
晚期PCM的管理优于早期的管理或没有PCM在管理和低温.
这种时间策略改善了患者在温度调节和疼痛管理方面的结果.

关键词:

麻醉麻醉是一种麻醉.低温症低温症是一个帕拉西托摩尔是一种可怕的药物.在外科手术期间的外科手术.在术后的术后生活.的着着着着着温度的温度的温度的温度的温度.

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