材料参数变量的影响预测冠状动脉生物机械环境通过不确定性量化
Caleb C Berggren1, David Jiang1, Y F Jack Wang1
1Department of Biomedical Engineering, University of Utah, Salt Lake City, UT, USA.
ArXiv
|February 12, 2024
概括
血管材料性质的不确定性显著影响预测的动脉应力,特别是在附带层. 本研究使用结合不确定性量化-有限元框架量化了这种变化.
科学领域:
- 计算生物力学计算力学
- 生物材料科学是生物材料的科学.
- 医疗模拟 医疗模拟
背景情况:
- 针对患者的具体建模需要可靠的模拟结果,可靠的输入不确定性.
- 对模拟结果的量化信心水平对于临床采用至关重要.
结论:
- 材料性质的变化极大地影响预测的动脉应力.
- 开发的管道有效地描述了计算生物力学中前模型的不确定性.
- 研究结果使用患者特定的冠状动脉模型进行了验证.
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