在第三级护理医院的亚临床甲状腺下降和甲状腺下降受试者的铁状况的比较研究
Thokati G Swapnika1, S S Sabitha Rani2, Satish Dipankar3
1Biochemistry, Krishna Institute of Medical Sciences (Hospital Group), Hyderabad, IND.
Cureus
|February 12, 2024
概括
亚临床甲状腺功能低下症显著增加缺铁性贫血的风险. 早期检测和管理至关重要,因为这两种情况往往并存并影响新陈代谢.
科学领域:
- 内分泌学 在内分泌学.
- 血液学 血液学 血液学
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 甲状腺激素对代谢平衡至关重要.
- 亚临床甲状腺功能低下症与缺铁性贫血和其他血液学问题有关.
- 早期的亚临床甲状腺功能低下症往往没有明显的症状.
研究的目的:
- 为了确定缺铁性贫血的患病率和严重程度.
- 为了研究亚临床甲状腺功能低下症和铁缺乏症之间的相关性.
- 评估亚临床甲状腺功能低下症对血液学参数的影响.
主要方法:
- 研究包括100名受试者:50名患有亚临床甲状腺功能低下症和50名健康对照.
- 使用自动化细胞计数器测量血红蛋白 (Hb) 水平.
- 评估甲状腺激素 (fT3,ft4,TSH) 和血清费里水平.
主要成果:
- 96%的亚临床甲状腺功能低下病例表现出缺铁性贫血.
- 86%的缺铁性贫血病例也有亚临床甲状腺功能低下症.
- 在TSH和Hb水平之间发现了显著的负相关性 (r=-0.86408),在某些情况下血清费里含量较低.
结论:
- 亚临床甲状腺功能低下症与显著增加的贫血患病率有关.
- 建议在亚临床甲状腺功能低下症中进行常规铁缺乏症查,以早期检测和管理.
- 显而易见的和亚临床的甲状腺功能低下症都被确定为缺铁性贫血的危险因素.
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